Prague startup directory
Hand-picked startups, investors, and ecosystem operators in Prague, with a custom city illustration in europe-startup-guide.com brand colors.
Showing 21–40 of 58 Prague · Czech Republic
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FrontKon 2026 (Oct 2026)
FrontKon is Prague's frontend conference, returning to O2 Universum with more than 30 talks across three stages plus workshops and around 900 attendees. The bilingual programme (Czech with English interpretation for international speakers) goes beyond frontend basics to cover web technologies, accessibility, architecture, and AI.
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GUG.cz
GUG.cz is the Czech Google Developer Group community and organiser of DevFest.cz, Prague's community developer conference. The volunteer-run organisation hosts meetups and an annual conference covering AI, Android, web, cloud, Flutter, security, and open source for the local developer community.
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Hedepy
Hedepy is an online therapy platform connecting patients with certified psychotherapists via video. It has expanded across more than ten European markets, offering multilingual access and flexible scheduling. The service addresses mental health capacity shortages by making therapy easier to access and scale. By 2026, Hedepy is a leading Czech health-tech company in digital mental health.
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Innovation Week 2026
The largest Czech innovation conference, in its 11th edition at ČSOB Campus, with 4 stages, 400+ speakers, and ~15,000 attendees covering AI, new technologies, and sustainability, plus a startup-investor matchmaking program.
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Inventoro
Inventoro provides AI-driven sales forecasting and inventory optimization for SMB retailers. The platform recommends what to order, when to reorder, and how to reduce dead stock, helping merchants improve margins. It integrates with POS and ecommerce systems to automate demand planning without enterprise complexity. By 2026, Inventoro is a fast-growing Czech AI retail-tech company.
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Karel Zheng
General Partner at KAYA VC, the Prague-headquartered early-stage fund focused on Central and Eastern Europe, which closed a €70M fund in 2025. He joined KAYA in 2018, founded a B2B SaaS startup in between, and now invests from pre-seed to Series A in AI, developer tools and vertical software.
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KAYA Ventures
KAYA is a Prague-based venture capital firm that invests early in ambitious founders building category-defining technology companies, staying involved from inception through to market leadership. Operating as an equal partnership, it backs Central European and international startups across software and deep tech.
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Keboola
Keboola provides an all-in-one data operations platform for connecting, cleaning, and orchestrating data pipelines. It is known for flexibility, modularity, and an enterprise-grade pay-as-you-go model. The company has been profitable for years and raised a late Series A to accelerate global expansion. By 2026, Keboola is a trusted DataOps layer for mid-market and enterprise customers.
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Liftago
Liftago is a Prague-based ride-hailing and delivery marketplace founded in 2012 that connects passengers and businesses with licensed professional taxi drivers and courier services. Unlike Uber and Bolt, Liftago works exclusively with regulated taxi operators, positioning itself as a compliant alternative in the Czech market. The platform expanded into last-mile delivery and B2B logistics, helping restaurants and retailers fulfill same-day orders. Liftago has become one of the most widely used mobility apps in Prague, with a strong network of professional drivers and fleet partnerships.
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Malcom Finance
Malcom Finance (formerly 4Trans) provides factoring and financing for truck drivers and logistics SMEs. Its underwriting leverages real-time telematics and operational data to assess risk more accurately than traditional banks. This enables faster payouts and more flexible credit for transport operators who are cash-flow constrained. By 2026, Malcom is a fast-growing Czech fintech focused on the logistics economy.
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Manta
Manta is a data lineage and metadata-management platform that gives organisations visibility into their data environments by automatically scanning the data stack and mapping data flows, sources, transformations and dependencies. By generating this lineage and an audit trail, it helps businesses trace where data originated and how it evolved, and can discover and anonymise sensitive data to reduce regulatory risk. Founded in Prague in 2016, Manta was acquired by IBM in October 2023 and its data lineage was integrated into IBM's watsonx data and AI governance portfolio.
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Manuel Matuzović
Web developer, author, and trainer specialising in web accessibility, HTML, and CSS. A recognised voice in the accessibility community and a confirmed speaker at FrontKon 2026 in Prague, where he covers building inclusive, standards-based web interfaces.
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Mews
Mews is a cloud-native property management system built to replace legacy hotel software with an API-first platform. It powers hotel operations from booking and pricing to payments and guest communications, enabling chains to modernize at speed. By 2026, Mews is aggressively acquiring smaller travel-tech vendors and expanding global enterprise contracts, positioning itself as the default operating system for modern hospitality. The company is a Czech-born unicorn with a strong international footprint and deep Prague engineering roots.
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Oddin.gg
Oddin.gg is a B2B provider of esports odds feeds, risk management, and trading tools. It supplies real-time probabilities for esports titles such as Counter-Strike and League of Legends, enabling betting operators to price markets reliably. The company has become a global leader in esports wagering infrastructure. By 2026, Oddin.gg is one of the Czech Republic’s most internationally recognized gaming-tech exports.
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Open Source Summit Europe 2026 (Oct 2026)
Open Source Summit Europe is the Linux Foundation's premier vendor-neutral conference for the global open-source ecosystem, featuring keynotes, breakout sessions, and a Solutions Showcase. The 2026 edition is hosted in Prague, convening maintainers, developers, technologists, and community leaders shaping the future of open source, with co-located events on the preceding days.
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Patron GO
AI-powered personal finance app that detects unnecessarily high payments and subscriptions in users' bank accounts and recommends better offers. Operating in Czechia and Slovakia, it has passed 350,000 users.
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Pavel Lukeš
Technology leader heading IT at Direct pojišťovna / Direct Technologies, where he led the rebuild of the insurer's core systems around AI and multi-agent delivery. A confirmed speaker at FrontKon 2026 in Prague on AI-first software delivery.
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Productboard
Productboard is a Prague-founded software company building one of the defining systems of record for modern product management. The platform helps teams collect customer feedback, connect it to feature requests, prioritize product decisions, and communicate roadmaps across engineering, sales, and leadership. That matters because product work often suffers from fragmented information spread across support systems, CRM notes, internal docs, and ad hoc spreadsheets. Productboard turns that sprawl into a more structured workflow for deciding what should be built and why. In the Central and Eastern European ecosystem, it is a particularly strong reference case because it proves that category-leading B2B SaaS products can emerge from Prague and scale globally while retaining a major engineering footprint in the region. It also occupies an important position in the software operating stack of growth companies, since fast-moving startups need better ways to align customer demand with product execution. As a result, Productboard is not only a Czech success story, but also a useful link between early-stage product discipline and later-stage organizational scale.
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Recombee
AI-powered real-time recommendation and personalized search engine offered as a SaaS API; uses 100+ proprietary ML models and the ReQL query language, serving media, streaming, e-commerce and marketplaces.
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Resistant AI
Resistant AI focuses on AI-driven fraud detection for financial services, specifically identifying manipulated documents used in KYC and onboarding. Its models detect fake paystubs, doctored IDs, and synthetic documents that bypass traditional checks. As digital fraud grows more sophisticated, Resistant AI has become a critical partner for fintechs and banks. By 2026, it is a leading Czech player in the FinTech security category.
